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Scientists prove: additional activity in the production of free of radicals. A new research result, supported by NSE, to internal causes of aging, has identified a previously unknown source of superoxide free radicals. Free radicals by external triggers, such as exposing the solar radiation, cigarette smoke, are long known to the skin cells and components of extracellular (lying outside the cell) matrix, including collagen and elastin, to damage. NSE and Purdue University scientists report on their new research findings of regarding age-related NADH oxidase (arNOX) this week in Kyoto, Japan, on the international investigative dermatology 2008, a major event for the latest information about the biology of the skin. Scientists explain the conclusive evidence that arNOX, an enzyme which is related to cell membranes, skin cells and is active. The arNOX activity increases considerably during the Advanced”years of approximately 45 to 70 years. A breakthrough discovery in understanding the aging is the identification of arNOX as the skin-Dungeness and its growing activity with age, “explains Dr.
med. Zoe Diana Draelos, research Chairman of Dermatology consulting services, the NSE Scientific Advisory Board member (NSE Scientific Advisory Board) and one of the authors of the study. Currently the dermatological research focuses on the correction of skin damage, after they are created. By recognizing the internal source of free radicals in the skin and if you closer to understanding, why and how they are produced, then our ability contributes, to address the basic mechanisms that are available, possibly in conjunction with external sources to the accelerated aging lead.”the detection of arNOX in the skin allows further insights into the potential revolutionary treatments for skin care. In particular, because its activity relating to the years, if the People are beginning to see how their skin loses its elasticity and firmness, and you notice the fading of her complexion and wrinkles,”notes Dr.
phil. Helen Knaggs on, Vice President of NSE global research and development (NSE global research and development). “If we can pursue innovative ways to curtail the activity of arNOX and especially the production of free radicals to stop, then we can talk on both sides of the equation: the damage caused by free radicals of external sources right, while at the same time prevents the production of free radicals from internal sources.” The study’s authors are Dale Kern, Chief Scientist at NSE, Dr. phil. Dorothy Morre, Professor of foods and nutrition at Purdue University, and Dr. phil. D. James Morre, Dow Honorary Professor in pharmaceutical chemistry of at Purdue University. Since 1999, the NSE and the Morres ENOX research have supported and promoted. About arNOX: The arNOX enzyme belongs to a class of newly discovered and certain ECTO-NOX (external NADH oxidase or ENOX)-proteins, which are stored on external (outer) cell membranes. ECTO-NOX proteins become increasingly active to generate additional metabolic energy, such as the age of mitochondria, and produce less energy. arNOX has been proven in all cells tested, including serum, saliva and then DermIS (DermIS) and the skin (epidermis). Its unique feature is that it generates superoxide on the cell surface, which is able to damage adjacent cells, lipoproteins and other structural components of the extracellular matrix of the skin, such as collagen and elastin. Other NOX categories include the tumor-NOX, viral NOX and the Basic or normal NOX. About the international investigative dermatology 2008 is the fifth joint meeting of the society of Investigative Dermatology (SID), the European society for Dermatology research (ESDR) and the Japanese society for Investigative Dermatology (JSID).
After implementing the SKV technology – device request (SKV technology reported on the 02.05.2013), the technicians of the SKV technology team Plauen one implemented new SKV Configurator. With customers, tests showed that the search time for the appropriate side channel blowers will be reduced on average half of the usual time. This has once again achieved an increase in customer satisfaction and improved the shopping experience of customers in the SKV technique online shop. Customers prefer simple configuration options in the online shop. The SKV Configurator enable customers in the situation, to set the selected parameters on the side channel blowers by clicking.
The SKV technology Configurator is similar to a car configurator in the automotive industry. The search became again decisively easier according to the desired side channel blowers. What was changed? The technology relies on the now proven system of “One Step to Conversion” on. With the aim of making the selection of the desired side channel blower with a single click, is consistently implemented. How does it work? Each side channel blowers has certain characteristics which determined its appearance and performance, for example, its size.
These parameters are laid down. The customer has specific parameter requests the device, which must be necessarily exists to fulfill a particular work. The SKV technology Configurator now has a logic in such a way, that the customer inputs are permanently matched with the parameters of machine stock. The Configurator is always exactly the questions that would be also a seller locally. In this way, customers choose safely and precisely to the desired machine. Should the machine not in stock, dodging the Configurator on the request mode and automatically creates a request to SKV technology. SKV technology service takes immediately to the customer request (opening times note!). What is the benefit for the customer? Customers save themselves at SKV time, which actually do not have technology. Cumbersome search in many different Online shops are no longer necessary because SKV technology immediately can meet either the machine request or a corresponding device implemented in due time on the market. The most important drive of the team by SKV technology is and remains the satisfaction of its customers. Customers save time and have clarity in the selection of the side channel blowers, and rely on the delivery time. What is implemented in the future in the SKV technology online shop? SKV technology – callback service against end of may 2013 when SKV technology of the callback service implemented. Problems in the implementation of side channel compressors in system solutions by the customer are not always alone can be solved. Systems become more complex and require the skills of an engineer experienced with the use of side channel compressors. The SKV applies technology callback service in action here. Customers get help! SKV will report technology. Contact: side channel blowers / SKV technology after the three mountains 60 08527 Plauen Tel.
The need for small – and micro remote work stations has evolved rapidly the new remote work unit of ACOS 711 with TETRA-modem with the integration of distributed generation in the distribution networks and the related expansion of local network stations in recent years. The IDS GmbH, specialist for network management, control systems, automation, telecontrol and communication technology, ACOS now offers with the standardized remote work unit 711 a cost-optimized solution for network operators, who can use private TETRA radio networks to the process data. To achieve the generation facilities and local network stations, utilities have to rely on public networks. The incurred costs, as well as the discussion on the security and availability of communication in critical infrastructures have led however, that more and more utilities invest in building their own networks. These are largely based on TETRA standards and serve both for the voice – and data communication. The IDS GmbH expanded its remote work product line of ACOS 7 series with ACOS 711 to another unit with integrated TETRA modem specially for small and Kleinstanwendungen.
It is suitable in particular for the following areas and tasks: power management for EEG/CHP Anlagen(z.B. PV-, Wind-, Biogas-Anlagen, BHKW,..) Local network stations in electrical distribution networks, water / wastewater sector (valve stations, pump stations, tank) Verkehrsbetriebe (mast switch, switch heaters, infrastructure) measuring systems (level equipment, environmental stations, radiation measurements, weather stations) General remote working applications (goals, object protection,..) It is transmitted using the standard protocols IEC 60870-5-101 in the TETRA-SDS-mode. For the coupling of the ACOS 711 manufacturer any at command and control centers comes the TETRA gateway ACOS 750 used. The device can be configured easily for any applications and for use in TETRA networks. Also a vorparametriertes according to customer specifications, ready device can be supplied on request. The IDS GmbH is a company IDS group. IDS group holding GmbH, the IDS group is a specialist in IT and automation solutions for smart grid and smart metering is geared for the German and European market of supply and waste management, its innovative portfolio of products and services on all aspects of the technical operation of the network, geo-data-based information processing and the counter being. With more than 630 qualified employees in the fields of development, distribution, manufacturing, project management and administration, the IDS Group achieved consolidated sales of about 90 million in 2012.